Duke Health hosted leaders from the U.S. Department of Health and Human Services, Microsoft, and UNC-Chapel Hill on May 23 to talk about next steps in making trustworthy health care artificial intelligence (AI) a reality. Introducing a panel discussion that he moderated, Michael Pencina, PhD, chief data scientist for Duke Health, said that AI poses a lot of exciting opportunities but also a lot of unknowns. “The question is — do I want the future my children will live in?” he said. Panelists pointed out the potential for AI to transform health care by freeing up providers to do the most high-value work. They also discussed how to reduce risks such loss of jobs, privacy risks, and introducing unintended biases in algorithms used in clinical care. Mary Klotman, MD, executive vice President for health affairs at Duke University and dean of the School of Medicine, opened and closed the event.